pentobarbital will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Monitor Carefully (two)pentobarbital will minimize the extent or result of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Sturdy CYP3A4 inducers may well lessen suvorexant efficacy; if enhanced suvorexant dose needed, do not exceed 20 mg/working day
pentobarbital will minimize the extent or result of tramadol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Reduced AUC of tramadol and the active metabolite (O-desmethyltramadol) when coadministered with robust CYP3A4 and CYP2B6 inducers
pentobarbital will reduce the level or effect of tipranavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will decrease the extent or influence of dienogest/estradiol valerate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Ladies must not pick out estradiol valerate/dienogest as their contraceptive although applying powerful CYP3A4 inducers due to opportunity lower in contraceptive efficacy.
pentobarbital will lower the extent or effect of pitolisant by affecting hepatic/intestinal click here enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Intently. Pitolisant exposure is lowered by fifty% if coadministered with powerful CYP3A4 inducers.
pentobarbital will lower the level or result of estrogens esterified by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will reduce the extent or outcome of prednisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will lower the level or effect of carvedilol by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep an eye on.
pentobarbital will lower the level or influence of clozapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will minimize the extent or outcome of itraconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Mysterious.
pentobarbital will reduce the extent or effect of darunavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will decrease the level or effect of larotrectinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the level or effect of lonafarnib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is actually a delicate CYP3A4 substrate. Coadministration with sturdy or moderate CYP3A4 inducers is contraindicated.